Ace2-KO

Nomenclature
C57BL/6-Ace2em1/IL
Cat. NO.ILKO-190906
Strain StateSperm

Gene Summary:

SynonymsACEH
NCBI ID59272
MGI ID
Ensembl IDENSG00000130234
Human OrthologsACE2

Research Application:

Regulation of cardiovascular and renal function, as well as fertility , Cardiac contraction, colitis, cardiovascular and renal function, and fertility

Description:

Humanized Gene Knockout Strategy

landingpage-asko-190906-ace2-ko-mouse-1

PCR Gel Electrophoresis to Genotype Recombinant F1 Mice

Figure 1. In WT and HE mice, the ability of P1/P2 primers to amplify large bands does not affect the interpretation of the results as the primers were designed to amplify KO bands.

WT: P1/P2: 11152bp, P3/P4: 779bp

HE: P1/P2: 11152bp and 1.6 kb, P3/P4: 779bp

HO: P1/P2: 1.6 kb, P3/ P4: no product