Cre recombinase tool
Ace2-2A-CreERT2
Ace2-2A-CreERT2
Nomenclature
C57BL/6-Ace2em2(2A-CreERT2-WPRE-polyA)/IL
Cat. NO.ILKI-200187
Strain StateSperm
Gene Summary:
| Synonyms | ACEH |
| NCBI ID | 59272 |
| MGI ID | |
| Ensembl ID | ENSG00000130234 |
| Human Orthologs | ACE2 |
Research Application:
Description:
A 2A-CreERT2-WPRE-polyA expression cassette was knocked into the Ace2 gene stop codon site. Ace2 encodes angiotensin I converting enzyme 2. When crossed with a strain carrying a gene flanked by loxP sites, the flanked gene will be removed in cells expressing Cre. This strain is useful for studying lung injury and kidney disease caused by SARS coronavirus infection.