R26-CAG-LSL-GiDREADD(hM4Di)-2A-mCitrine

Nomenclature
C57BL/6-Gt(ROSA)26Sorem1(CAG-LSL-HA-GiDREADD(hM4Di)-2A-mCitrine-WPRE-pA)/IL
Cat. NO.ILKI-190093
Strain StateSperm

Gene Summary:

SynonymsR26, ROSA26, AV258896, Gtrgeo26, Gtrosa26, Thumpd3as1
NCBI ID14910
MGI ID104735
Ensembl IDENSMUSG00000086429
Human Orthologs

Research Application:

Chemical Genetics studies. The inhibitory GiDREADD(hM4Di) could silence the activity of neurons following administration of CNO.

Description:

These mice harbor a CAG-LSL-HA-GiDREADD(hM4Di)-2A-mCitrine-WPRE-pA cassette in the Rosa26 locus generated by homologous recombination.