Slc17a6-CreERT2

Nomenclature
C57BL/6-Slc17a6em2(CreERT2)/IL
Cat. NO.ILKI-190011
Strain StateSperm

Gene Summary:

SynonymsDNPI, Vglut2, 2900073D12Rik
NCBI ID140919
MGI ID2156052
Ensembl IDENSMUSG00000030500
Human OrthologsSLC17A6

Research Application:

Tool mice

Description:

This tamoxifen-inducible Slc17a6-CreERT2 tool mouse model was established by inserting a 2A-CreERT2-WPRE-polyA co-expression cassette into the stop codon of Slc17a6 gene.

Validation Data

landingpage-aski-190011-Slc17a6-CreERT2-ki-mouse-1

Figure 1: Expression Pattern of Tomato in Slc17a6-CreERT2 +/-, R26- tdTomato+/- mice.

CreERT2-mediated recombination in excitatory glutamatergic neuron cell bodies of Slc17a6-CreERT2+/-, R26-tdTomato+/- mice. Slc17a6-CreERT2 mice may be used to generate conditional mutations for studying gain-or-loss of function and/or fate mapping related to glutamatergic neurons.