R26-CAG-LSL-hHER2-IRES-Luc-2A-EGFP

Nomenclature
C57BL/6-Gt(ROSA)26Sorem1(SA-2xpolyA-CAG-LSL-HER2-luciferase-EGFP)/IL
Cat. NO.ILKI-190008
Strain StateSperm

Gene Summary:

SynonymsR26, ROSA26, AV258896, Gtrgeo26, Gtrosa26, Thumpd3as1
NCBI ID14910
MGI ID104735
Ensembl IDENSMUSG00000086429
Human Orthologs

Research Application:

Cancer

Description:

A SA-2xpolyA-CAG-LSL-HER2-IRES-Luciferase-2A-EGFP-WPRE-polyA cassette was inserted at the Rosa26 locus. When bred to a strain expressing Cre recombinase under control of various tissue specific promoters, Cre recombination deletes the LSL cassette and allows the expression of the HER2 protein.