Cancer research
Kras-LSL-G12D
Kras-LSL-G12D
Nomenclature
C57BL/6-Krasem4(LSL-G12D)/IL
Cat. NO.ILKI-190003
Strain StateLive
Gene Summary:
| Synonyms | Ki-ras, K-ras, Kras2, Kras-2 |
| NCBI ID | 16653 |
| MGI ID | 96680 |
| Ensembl ID | ENSMUSG00000030265 |
| Human Orthologs | KRAS |
Research Application:
Description:
Using CRISPR/Cas9 technology, exon2 of Kras were replaced by loxp-stop-loxp and exon2 containing G12D. When crossed with a Cre recombinase-expressing strain, this strain is useful in studies of cancer and development.