Tumor research; drug screening
R26-CAG-LSL-hNRF2-IRES-Luc-2A-tdTomato
R26-CAG-LSL-hNRF2-IRES-Luc-2A-tdTomato
Nomenclature
C57BL/6-Gt(ROSA)26Sorem1(CAG-LSL-NRF2-IRES-luciferase-2A-tdTomato)/IL
Cat. NO.ILKI-18050
Strain StateSperm
Gene Summary:
| Synonyms | R26, ROSA26, AV258896, Gtrgeo26, Gtrosa26, Thumpd3as1 |
| NCBI ID | 14910 |
| MGI ID | 104735 |
| Ensembl ID | ENSMUSG00000086429 |
| Human Orthologs |
Research Application:
Description:
A SA-2xpolyA-CAG-LSL-human NRF2-IRES-luciferase-2A-tdTomato-wpre-polyA cassette was knocked into the mouse Rosa26 locus. This strain of mice can be mated with mice expressing Cre recombinase to express human NRF2 and a reporter gene in certain cells or tissues that expressing Cre recombinase.