Lyz2-2A-CreERT2

Nomenclature
C57BL/6-Lyz2em1(2A-CreERT2-WPRE-pA)/IL
Cat. NO.ILKI-18018
Strain StateLive

Gene Summary:

SynonymsLys, Lzm, Lzp, Lysm, Lyzs, Lyzf2, Lzm-s1, AI326280
NCBI ID17105
MGI ID96897
Ensembl IDENSMUSG00000069516
Human Orthologs

Research Application:

Cre recombinase tool

Description:

A 2A-CreERT2-WPRE-pA coexpression cassette is inserted befor the stop codon of mouse Lyz2 gene via homologous recombination to establish a tamoxifen inducible Lyz2-CreERT2 tool stain. This strain can be used to knockout target gene in Lyz2+ cells after tamoxifen treatment when crossed with mice which carry loxp sites flanking target gene.