Cd2-2A-CreERT2

Nomenclature
C57BL/6-Cd2em1(2A-CreERT2-WPRE-pA)/IL
Cat. NO.ILKI-18017
Strain StateLive

Gene Summary:

SynonymsLy37, LFA-2, Ly-37
NCBI ID12481
MGI ID88320
Ensembl IDENSMUSG00000027863
Human OrthologsCD2

Research Application:

Cre recombinase tool

Description:

Model Description

A 2A-CreERT2-WPRE-pA coexpression cassette is inserted before the stop codon of mouse Cd2 gene via homologous recombination to establish a tamoxifen inducible Cd2-CreERT2 tool stain. This strain can be used to knockout target gene in T cells and B cells after tamoxifen treatment when crossed with mice which carry loxp sites flanking target gene.

Validation Data

landingpage-aski-18017-Cd2-2A-CreERT2-ki-mouse-1

Figure 1. The result shows that expression pattern of RFP in T cells of Cd2-(2A-CreERT2-WPRE-pA), RFP.