Recombinase tool
Aplnr-2A-DreERT2
Aplnr-2A-DreERT2
Nomenclature
C57BL/6-Aplnrem1(2A-DreERT2)/IL
Cat. NO.ILKI-00132
Strain StateEmbryo
Gene Summary:
| Synonyms | APJ, Agtrl1, msr/apj |
| NCBI ID | 23796 |
| MGI ID | 1346086 |
| Ensembl ID | ENSMUSG00000044338 |
| Human Orthologs | APLNR |
Research Application:
Description:
A 2A-DreERT2-SV40polyA coexpression cassette is inserted befor the stop codon of mouse Aplnr gene via homologous recombination to establish a tamoxifen inducible Aplnr-DreERT2 tool stain. This strain can be used to knockout target gene in Aplnr+ cells after tamoxifen treatment when crossed with mice which carry rox sites flanking target gene.