Immunotherapy, drug screening
IL18BP
IL18BP
Nomenclature
C57BL/6-Il18bpem1(hIL18BP)/IL
Cat. NO.ILHU-210039
Strain StateLive
Gene Summary:
| Synonyms | MC54L, Igifbp, IL-18BP |
| NCBI ID | 16068 |
| MGI ID | 1333800 |
| Ensembl ID | ENSMUSG00000070427 |
| Human Orthologs | IL18BP |
Research Application:
Description:
The endogenous mice Il18bp gene was replaced by human IL18BP gene.
Validation Data
Figure1. Detection of IL18BP expression in thymus and liver by RT-PCR.
Wild type: only one band at 354 bp with primers F1/R1 (mIl18bp),Heterozygous: one band at 354 bp with primers F1/R1 (mIl18bp) and one band at 220 bp with primers F2/R2 (hIL18BP), Abbr.. M, DNA marker, HO, homozygous, HE, heterozygous, WT, wild type.
Figure 2. Detection of IL18BP expression in thymus and liver by RT-PCR.
Wild type: only one band at 354 bp with primers F1/R1(mIl18bp), Homozygous: only one band at 220 bp with primers F2/R2(hIL18BP), Abbr. M, DNA marker, HO, homozygous, HE, heterozygous, WT, wild type.
Figure 3. Detection of hIL18BP expression in serum by ELISA.
Abbr. HO, homozygous, HE, heterozygous, WT, wild type.
Figure 4. Detection of mIL18BP expression in serum by ELISA.
Abbr. HO, homozygous, HE, heterozygous, WT, wild type.
Figure 5. Detection of hIL18BP expression in serum by ELISA (n=3).
Abbr. HO, homozygous, HE, heterozygous, WT, wild type.
Figure 6. Detection of mIL18BP expression in serum by ELISA.
Abbr. HO, homozygous, HE, heterozygous, WT, wild type.