IL18

Nomenclature
C57BL/6-Il18tm1(hIL18)/IL
Cat. NO.ILHU-210038
Strain StateEmbryo

Gene Summary:

SynonymsIgif, Il-18
NCBI ID16173
MGI ID107936
Ensembl IDENSMUSG00000039217
Human OrthologsIL18

Research Application:

Immunotherapy, drug screening

Description:

The endogenous mice Il18 gene was replaced by human IL18 gene.

Validation Data

landingpage-ashu-210038-IL18-hu-icpmouse-1

Figure1. Detection of IL18 expression in intestine, colon and spleen by RT-PCR.

Wild type: only one band at 305 bp with primers F1/R1 (mIl18), Homozygous: only one band at 265 bp with primers F2/R2 (hIL18). Abbr. M, DNA marker, HO, homozygous, HE, heterozygous, WT, wild type.

Figure 2. Detection of hIL18 expression in serum by ELISA (n=3).

Abbr. HO, homozygous, HE, heterozygous, WT, wild type.

Figure 3. Detection of mIL18 expression in serum by ELISA (n=3).

Abbr. HO, homozygous, HE, heterozygous, WT, wild type.