EPCAM

Nomenclature
C57BL/6-Epcamtm1(hEPCAM)/IL
Cat. NO.ILHU-210032
Strain StateEmbryo

Gene Summary:

SynonymsEGP, Ly74, gp40, CD326, EGP-2, TROP1, Egp314, Ep-CAM, EpCAM1, Tacsd1, GA733-2, Tacstd1
NCBI ID17075
MGI ID106653
Ensembl IDENSMUSG00000045394
Human OrthologsEPCAM

Research Application:

Immunotherapy, drug screening

Description:

Validation Data

landingpage-ashu-210032-epcam-hu-icpmouse-1

Figure1. Analysis of mouse EPCAM and human EPCAM protein expression in the large intestine by IHC.

Both the EPCAM humanized heterozygous mouse and wild type express mouse EPCAM in the mucosal epithelial membranes, and the humanized heterozygous mouse expresses human EPCAM in the crypts significantly.

Figure 2. Analysis of mouse EPCAM and human EPCAM protein expression in the small intestine by IHC.

Both the EPCAM humanized heterozygous mouse and wild type express mouse EPCAM in the mucosal epithelial membranes, and the humanized heterozygous mouse expresses human EPCAM in the crypts significantly.