Drug screening
F12
F12
Nomenclature
C57BL/6-F12tm1(hF12)/IL
Cat. NO.ILHU-210017
Strain StateLive
Gene Summary:
| Synonyms | HAF, FXII |
| NCBI ID | 58992 |
| MGI ID | 1891012 |
| Ensembl ID | ENSMUSG00000021492 |
| Human Orthologs | F12 |
Research Application:
Description:
The endogenous mice F12 gene was replaced by human F12 gene.
Validation Data
Figure 1. Detection of F12 expression in liver by RT-PCR.
Wild type: only one band at 318 bp with primers F1/R1 (mF12), Homozygous: only one band at 274 bp with primers F2/R2 (hF12), Abbr. M, DNA marker, HO, homozygous, HE, heterozygous, WT, wild type.
Figure 2. Detection of hF12 expression in serum by ELISA (n=2).
Abbr. HO, homozygous, HE, heterozygous, WT, wild type.
Figure 3. Detection of mF12 expression in serum by ELISA (n=2).
Abbr. HO, homozygous, HE, heterozygous, WT, wild type.