HLA-DPB1*04:01

Nomenclature
C57BL/6-H2-Ab1em1(hHLA-DPB1*04: 01)/IL
Cat. NO.ILHU-210011
Strain StateSperm

Gene Summary:

SynonymsIab, Ia2, Ia-2, Abeta, H-2Ab, H2-Ab, Rmcs1, I-Abeta
NCBI ID14961
MGI ID103070
Ensembl IDENSMUSG00000073421
Human OrthologsHLA-DQB1

Research Application:

Immunotherapy, drug screening

Description:

The endogenous mice H2-Ab1 gene was replaced by human HLA-DPB1*04:01 gene.

Validation Data

landingpage-ashu-210011-HLA-DPB1*04:01-hu-icpmouse1

Figure 1. Detection of HLA-DPB1*04:01 expression in spleen by RT-PCR. Wild type: only one band at 372 bp with primers F1/R1 (mH2-Ab1), Heterozygous: one band at 372 bp with primers F1/R1 (mH2-Ab1) and one band at 362 bp with primers F2/R2 (hHLA-DPB1*04:01), Abbr.. M, DNA marker, HO, homozygous, HE, heterozygous, WT, wild type.