Immune-related, drug screening
CD20 (2)
CD20 (2)
Nomenclature
C57BL/6-Ms4a1tm2 (hCD20)/IL
Cat. NO.ILHU-200114
Strain StateLive
Gene Summary:
| Synonyms | Cd20, Ly-44, Ms4a2, AA960661 |
| NCBI ID | 12482 |
| MGI ID | 88321 |
| Ensembl ID | ENSMUSG00000024673 |
| Human Orthologs | CD20 |
Research Application:
Description:
Validation Data
Figure1. Human CD20 expression on B cells is confirmed by FACS analysis in the heterozygous humanized CD20 mice. The heterozygous KI animal expresses both human and murine CD20 on CD19+ B cells.
Figure 2. Human CD20 expression on CD45+ cells is confirmed by FACS analysis in WT, heterozygous, and homozygous humanized CD20 mice. The WT animal expresses mouse CD20 on CD45+ cells, and the homozygous KI expresses human CD20, while the heterozygous KI expresses both human and murine CD20.