Immunotherapy, drug screening
PD-1 & SIRPA (2)
PD-1 & SIRPA (2)
Nomenclature
C57BL/6 - Pdcd1em1(hPDCD1)Sirpaem1(hSIRPA)/IL
Cat. NO.ILHU-2000089
Strain StateEmbryo
Gene Summary:
| Synonyms | PD-1, Pdc1, Ly101, Bit, P84, SIRP, SHP-1, CD172a, Ptpns1, SHPS-1, AI835480 |
| NCBI ID | 18566, 19261 |
| MGI ID | 104879, 108563 |
| Ensembl ID | ENSMUSG00000026285, ENSMUSG00000037902 |
| Human Orthologs | PDCD1, SIRPA |
Research Application:
Description:
This PD-1 and SIRPA double Knock-in strain is established by crossing PD-1-HU and SIRPA-HU mice together. These double double Knock-in mouse models can be useful for evalueting the efficacy of potential immunotherapy drug combinations.