Cytokine humanization model, drug screening
IL12A
IL12A
Nomenclature
C57BL/6-Il12atm3(hIL12A)/IL
Cat. NO.ILHU-2000056
Strain StateEmbryo
Gene Summary:
| Synonyms | p35, Ll12a, Il-12a, IL-12p35 |
| NCBI ID | 16159 |
| MGI ID | 96539 |
| Ensembl ID | ENSMUSG00000027776 |
| Human Orthologs | IL12A |
Research Application:
Description:
The endogenous mouse Il12a gene was replaced by human IL12A gene.
Validation Data
Figure 1. Detection of IL12A expression in spleen by RT-PCR. Wild type: only one band at 198 bp with primers F1/R1 (mIl12a), Homozygous: only one band at 488 bp with primers F2/R2 (hIL12A), Abbr.. M, DNA marker, HO, homozygous, HE, heterozygous, WT, wild type.