IFNGR1

Nomenclature
C57BL/6-Ifngr1tm(hIFNGR1)/IL
Cat. NO.ILHU-190076
Strain StateEmbryo

Gene Summary:

SynonymsIfgr, CD119, Ifngr, Nktar, IFN-gammaR
NCBI ID15979
MGI ID107655
Ensembl IDENSMUSG00000020009
Human OrthologsIFNGR1

Research Application:

Immunotherapy, cancer research, drug screening

Description:

The endogenous mouse Ifngr1 gene was replaced by human IFNGR1 gene.

Validation Data

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Figure 1. Detection of IFNGR1 expression by RT-PCR. Wild type: only one band at 271 bp with primers F2/R2 (mIfngr1), Homozygous: only one band at 296 bp with primers F1/R1 (hIFNGR1), Abbr.. M, DNA marker, HO, homozygous, HE, heterozygous, WT, wild type.

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Figure 2. Validation of hCD119 (IFNGR1) expression in blood by FACS.

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Figure 3. Validation of hCD119 (IFNGR1) expression in spleen by FACS.

Figure 4. Validation of hCD119 (IFNGR1) expression in bone marrow by FACS.