Immunotherapy, cancer research, drug screening
CD27 (2)
CD27 (2)
Nomenclature
C57BL/6-Cd27tm3(hCD27)/IL
Cat. NO.ILHU-190035
Strain StateEmbryo
Gene Summary:
| Synonyms | Cd27, S152, Tnfrsf7, Tp55 |
| NCBI ID | 21940 |
| MGI ID | 88326 |
| Ensembl ID | ENSMUSG00000030336 |
| Human Orthologs | CD27 |
Research Application:
Description:
Humanized Strategy
Validation Data
Figure 1. Detection of CD27 expression in peripheral blood cells of humanized CD27 mice.
The expression of human CD27 was detected by FACS. The results showed that the active expression of human CD27 can be detected in both activated CD4+ and CD8+ T lymphocytes collected from humanized CD27 mice.
Figure 2. Analysis of human CD27 expression in bone marrow by FACS . The homozygous KI mouse expresses human CD27 on CD4+ T cells.
Figure 3. Analysis of human CD27 expression in the spleen by FACS . The homozygous KI mouse expresses human CD27 on CD4+ T cells.