IL5

Nomenclature
C57BL/6 - Il5tm3(hIL5)/IL
Cat. NO.ILHU-190001
Strain StateEmbryo

Gene Summary:

SynonymsIl-5
NCBI ID16191
MGI ID96557
Ensembl IDENSMUSG00000036117
Human OrthologsIL5

Research Application:

Immune-related research

Description:

This IL5 humanized mouse model was established by replacing the mouse Il5 gene coding exons and introns with the human TLR9 corresponding sequence by homologous recombination.

Validation Data

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Figure1. Detection of IL-5 expression in thymus by RT-PCR. Wild type: only one band at 206 bp with primers F1/R1(mIl-5),Homozygous: only one band at 207 bp with primers F2/R2(hIL-5), Abbr.. M, DNA marker, HO, homozygous, HE, heterozygous, WT, wild type.

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Figure 2. Expression of human IL5 in the Serum of IL5-HU homozygous mice is detected by Elisa.

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Figure 3. Expression of murine IL5 in the Serum of IL5-HU homozygous mice is detected by Elisa.