SIRPA (2)

Nomenclature
C57BL/6 - Sirpatm2(hSIRPA)/IL
Cat. NO.ILHU-18015
Strain StateLive

Gene Summary:

SynonymsBit, P84, SIRP, SHP-1, CD172a, Ptpns1, SHPS-1, AI835480
NCBI ID19261
MGI ID108563
Ensembl IDENSMUSG00000037902
Human OrthologsSIRPA

Research Application:

Immunotherapy, drug screening

Description:

Humanized Gene Knock-in Strategy

SIRPA Humanized Immune Checkpoint Mouse Model
SIRPA Humanized Immune Checkpoint Mouse Model

Expression of hSIRPA Expression in PBMC of Heterozygous Mice Using FACS

SIRPA Humanized Immune Checkpoint Mouse Model

Efficacy of Anti-CD47 Treatment in a MC38 Syngeneic Tumor Model of SIRPA-HU Mice

SIRPA Humanized Immune Checkpoint Mouse Model

Efficacy of Anti-CD47 Treatment in a MC38 Syngeneic Tumor Model of SIRPA/CD47 Double Humanized Mice