CD3E

Nomenclature
C57BL/6-Cd3eem1(hCD3E)/IL
Cat. NO.ILHU-00114
Strain StateLive

Gene Summary:

SynonymsCD3, T3e, AI504783, CD3epsilon
NCBI ID12501
MGI ID88332
Ensembl IDENSMUSG00000032093
Human OrthologsCD3E

Research Application:

Immunotherapy, cancer research, drug screening

Description:

Humanized Gene Knock-in Strategy

CD3E Humanized Immune Checkpoint Mouse Model

Validation Data

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Figure 1. The expression of human CD3E in the peripheral blood cells derived from heterozygous or homozygous humanized mice was confirmed by FACS.

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Figure 2. Detection of T cell subsets in the peripheral blood cells derived from heterozygous or homozygous CD3E humanized mice.

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Figure 3. Detection of B and NK cells in the peripheral blood cells derived from heterozygous or homozygous CD3E humanized mice.

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Figure 4. In vitro T cell activation with heterozygous or homozygous CD3E humanized mice.