Immunotherapy, cancer research, drug screening
IL17A
IL17A
Nomenclature
C57BL/6 - Il17aem1(hIL17A)/IL
Cat. NO.ILHU-00042
Strain StateEmbryo
Gene Summary:
| Synonyms | Il17, Ctla8, IL-17, Ctla-8, IL-17A |
| NCBI ID | 16171 |
| MGI ID | 107364 |
| Ensembl ID | ENSMUSG00000025929 |
| Human Orthologs | IL17A |
Research Application:
Description:
The endogenous mouse Il17a gene was replaced by human IL17A gene.
Validation Data
Figure 1. Detection of IL-17A expression in Large Intestine by RT-PCR. Wild type: only one band at 100 bp with primers F1/R1 (mIl-17a), Homozygous: only one band at 121 bp with primers F2/R2 (hIL-17A), Abbr.. M, DNA marker, HO, homozygous, HE, heterozygous, WT, wild type.
Figure 2. Expression of human IL17A in cell supernatant derived from splenocytes of IL17A-HU homozygous mice is detected by Elisa.