Casp8-Flox

Nomenclature
C57BL/6-Casp8em1(flox)/IL
Cat. NO.ILCKO-190003
Strain StateLive

Gene Summary:

SynonymsMACH, Mch5, FLICE, CASP-8
NCBI ID12370
MGI ID1261423
Ensembl IDENSMUSG00000026029
Human OrthologsCASP8

Research Application:

Cancer research, Apoptosis

Description:

These Casp8 flox mice possess loxP sites flanking exons 4 CRISPR/Cas mediated recombination. When crossed with a Cre recombinase-expressing strain, this strain is useful in eliminating tissue-specific conditional expression of the gene.