Tool mice
Slc17a6-CreERT2
Slc17a6-CreERT2
Nomenclature
C57BL/6-Slc17a6em2(CreERT2)/Asc
Cat. NO.ASKI-190011
Strain State
Gene Summary:
| Synonyms | DNPI, Vglut2, 2900073D12Rik |
| NCBI ID | 140919 |
| MGI ID | 2156052 |
| Ensembl ID | ENSMUSG00000030500 |
| Human Orthologs | SLC17A6 |
Research Application:
Description:
This tamoxifen-inducible Slc17a6-CreERT2 tool mouse model was established by inserting a 2A-CreERT2-WPRE-polyA co-expression cassette into the stop codon of Slc17a6 gene.
Validation Data
Figure 1: Expression Pattern of Tomato in Slc17a6-CreERT2 +/-; R26- tdTomato+/- mice.
CreERT2-mediated recombination in excitatory glutamatergic neuron cell bodies of Slc17a6-CreERT2+/-; R26-tdTomato+/- mice. Slc17a6-CreERT2 mice may be used to generate conditional mutations for studying gain-or-loss of function and/or fate mapping related to glutamatergic neurons.
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