Gba-(D427V)

Nomenclature
C57BL/6J-Gbaem1(D427v)Asc
Cat. NO.ASKI-18060
Strain State

Gene Summary:

SynonymsGC; GBA1; GLUC; GCase; betaGC
NCBI ID14466
MGI ID95665
Ensembl IDENSMUSG00000028048
Human OrthologsGBA

Research Application:

Immunotherapy

Description:

The D427V point mutation is located in exon9 of mouse Gba gene. This Gba point mutation mouse model was established by introduce an A>T transversion at the 119th nucleotide of exon9 via CRISPR-mediated gene editing technology.