Npc1-(I1060T)

Nomenclature
C57BL/6J-Npc1em1(I1060T)Asc
Cat. NO.ASKI-18059
Strain State

Gene Summary:

Synonymsspm; lcsd; C85354; nmf164; D18Ertd139e; D18Ertd723e; A430089E03Rik
NCBI ID18145
MGI ID1097712
Ensembl IDENSMUSG00000024413
Human OrthologsNPC1

Research Application:

Immunotherapy

Description:

The I1060T point mutation is located in exon21 of mouse Npc1 gene. This Npc1 point mutation mouse model was established by introduce a T>C transversion at the 138th nucleotide of exon21 via CRISPR-mediated gene editing technology.