Immunotherapy
R26-(EZH2)
R26-(EZH2)
Nomenclature
C57BL/6J-Gt(ROSA)26Sorem1(CAG-LSL-EZH2-IRES-luciferase-2A-tdTomato)Asc
Cat. NO.ASKI-18053
Strain State
Gene Summary:
| Synonyms | |
| NCBI ID | |
| MGI ID | |
| Ensembl ID | |
| Human Orthologs | EZH2 |
Research Application:
Description:
A SA-2xpolyA-CAG-Loxp-Stop-Loxp-human EZH2 cDNA-IRES-luciferase-2A-tdTomato-wpre-polyA cassette was knocked into the mouse Rosa26 locus by CRISPR/Cas9 gene editing technology. This strain of mice can be mated with mice expressing Cre recombinase so that human EZH2 could be expressed after exposure to Cre recombinase.