Immunotherapy
R26-(C-MET)
R26-(C-MET)
Nomenclature
C57BL/6J-Gt(ROSA)26Sorem1(CAG-LSL-c-MET-IRES-luciferase-2A-tdTomato)Asc
Cat. NO.ASKI-18052
Strain State
Gene Summary:
| Synonyms | |
| NCBI ID | |
| MGI ID | |
| Ensembl ID | |
| Human Orthologs | C-MET |
Research Application:
Description:
A SA-2xpolyA-CAG-Loxp-Stop-Loxp-human cMET-IRES-luciferase-2A-tdTomato-wpre-polyA cassette was knocked into the mouse Rosa26 locus by CRISPR/Cas9 gene editing technology. This strain of mice can be mated with mice expressing Cre recombinase so that human C-MET could be expressed after exposure to Cre recombinase.