Immunotherapy
R26-(NRF2)
R26-(NRF2)
Nomenclature
C57BL/6J-Gt(ROSA)26Sorem1(CAG-LSL-NRF2-IRES-luciferase-2A-tdTomato)Asc
Cat. NO.ASKI-18050
Strain State
Gene Summary:
| Synonyms | |
| NCBI ID | |
| MGI ID | |
| Ensembl ID | |
| Human Orthologs | NRF2 |
Research Application:
Description:
A SA-2xpolyA-CAG-LSL-human NRF2-IRES-luciferase-2A-tdTomato-wpre-polyA cassette was knocked into the mouse Rosa26 locus by CRISPR/Cas9 gene editing technology. This strain of mice can be mated with mice expressing Cre recombinase to express human NRF2 and a reporter gene in certain cells or tissues that expressing Cre recombinase.