Immunotherapy
R26-(CAG-LSL-Itpr1-Flag-tdTomato)
R26-(CAG-LSL-Itpr1-Flag-tdTomato)
Nomenclature
C57BL/6J-Gt(ROSA)26Sorem(CAG-LSL-Itpr1-3xFlag-IRES-tdTomato-wpre-polyA)Asc
Cat. NO.ASKI-18046
Strain State
Gene Summary:
| Synonyms | InsP3R type I, Ip3r, IP3R1, Itpr-1, opt, P400, Pcp1, Pcp-1, wblo |
| NCBI ID | 16438 |
| MGI ID | 96623 |
| Ensembl ID | ENSMUSG00000030102 |
| Human Orthologs | ITPR1 |
Research Application:
Description:
These mice harbor a loxP-flanked STOP cassette preventing transcription of a CAG promoter-driven Itpr1-3xFlag-IRES-tdTomato expression cassette. The targeted mutation was inserted into the Gt(ROSA)26Sor locus by CRISPR/Cas mediated homologous recombination.