Immunotherapy
C57BL/6J-Lyz2em1(2A-CreERT2-WPRE-pA)Asc
C57BL/6J-Lyz2em1(2A-CreERT2-WPRE-pA)Asc
Nomenclature
ASKI-18018
Cat. NO.ASKI-18018
Strain State
Gene Summary:
| Synonyms | Lys; Lzm; Lzp; Lysm; Lyzs; Lyzf2; Lzm-s1; AI326280 |
| NCBI ID | 17105 |
| MGI ID | 96897 |
| Ensembl ID | ENSMUSG00000069516 |
| Human Orthologs |
Research Application:
Description:
A 2A-CreERT2-WPRE-pA coexpression cassette is inserted befor the stop codon of mouse Lyz2 gene via homologous recombination to establish a tamoxifen inducible Lyz2-CreERT2 tool stain. This strain can be used to knockout target gene in Lyz2+ cells after tamoxifen treatment when crossed with mice which carry loxp sites flanking target gene.