R26-(CAG-LSL-dCas9-VPR-IRES-EGFP-WPRE-pA)

Nomenclature
C57BL/6J-Gt(ROSA)26Sorem1(CAG-LSL-dCas9-VPR-IRES-EGFP-WPRE-pA)
Cat. NO.ASKI-18004
Strain State

Gene Summary:

Synonyms
NCBI ID
MGI ID
Ensembl ID
Human Orthologs

Research Application:

Immunotherapy

Description:

These mice harbor a CAG-LSL-dCas9-VPR(VP64-p65-Rta)-eGFP-pA conditional expression cassette in mouse Rosa26 loci by CRISPR/Cas mediated homologous recombination. This strain can be used in CRISPR mediated target gene transcriptional activation (CRISPRa).