R26-(CAG-LNL-Cas9-IRES-Luciferase-pA)1

Nomenclature
C57BL/6J-Gt(ROSA)26Sorem1(CAG-LNL-Cas9-IRES-Luciferase-pA)
Cat. NO.ASKI-18002
Strain State

Gene Summary:

Synonyms
NCBI ID
MGI ID
Ensembl ID
Human Orthologs

Research Application:

Immunotherapy

Description:

These mice harbor a loxP-flanked STOP cassette preventing transcription of a CAG promoter-driven Cas9 gene followed by IRES-Luciferase coexpression cassette. The targeted mutation was inserted into the Rosa26 locus by homologous recombination.