Aplnr-DreERT2

Nomenclature
C57BL/6J-Aplnrem1(2A-DreERT2)Asc
Cat. NO.ASKI-00132
Strain State

Gene Summary:

SynonymsAgtrl1, apelin receptor, APJ, msr/apj
NCBI ID23796
MGI ID1346086
Ensembl IDENSMUSG00000044338
Human OrthologsAPLNR

Research Application:

Immunotherapy

Description:

A 2A-DreERT2-SV40polyA coexpression cassette is inserted befor the stop codon of mouse Aplnr gene via homologous recombination to establish a tamoxifen inducible Aplnr-DreERT2 tool stain. This strain can be used to knockout target gene in Aplnr+ cells after tamoxifen treatment when crossed with mice which carry rox sites flanking target gene.