R26-(ddCas9)

Nomenclature
C57BL/6-Gt(ROSA)26Sortm1(CAG-LNL-ddCas9)Asc
Cat. NO.ASKI-00063
Strain State

Gene Summary:

Synonyms
NCBI ID
MGI ID
Ensembl ID
Human Orthologs

Research Application:

Immunotherapy

Description:

These mice harbor a loxP-flanked STOP cassette preventing transcription of a CAG promoter-driven ddCas9. The targeted mutation was inserted into the Gt(ROSA)26Sor locus by CRISPR/Cas mediated homologous recombination.