R26-(Cas9)

Nomenclature
C57BL/6-Gt(ROSA)26Sortm1(CAG-LNL-Cas9)Asc
Cat. NO.ASKI-00038
Strain State

Gene Summary:

Synonyms
NCBI ID
MGI ID
Ensembl ID
Human Orthologs

Research Application:

Immunotherapy

Description:

These mice harbor a loxP-flanked STOP cassette preventing transcription of a CAG promoter-driven Cas9 gene. The targeted mutation was inserted into the Gt(ROSA)26Sor locus by homologous recombination. Cas9 is expressed when bred to mice that express Cre recombinase.