The endogenous mice Fas gene was replaced by human FAS gene.
Validation Data
Figure 1. Detection of FAS expression in thymus and lung by RT-PCR.
Wild type: only one band at 286 bp with primers F1/R1 (mFas);Heterozygous: one band at 286 bp with primers F1/R1 (mFas) and one band at 304 bp with primers F2/R2 (hFAS); Abbr.. M