Humanized Mouse Model HLA-A2
HLA-A2
HLA-A2
Nomenclature
Cat. NO.ASHU-204988
Strain State
Gene Summary:
| Synonyms | |
| NCBI ID | /m/o/mouse-model-20200122_88_7_25.jpg |
| MGI ID | |
| Ensembl ID | |
| Human Orthologs | ASHU-204988, HLA-A2, C57BL/6J-H2-D1em1(hHLA-A2)/Asc, GENE Synonyms H-2D, H2-D, H2-K1, Human Orthologs HLA-A, HLA-B, HLA-C, ENSMUSG00000073411, 95896, 14964, Background C57BL/6J, Coat Color Black, tumor research, drug screening |
Research Application:
Description:
The endogenous mice H2-D1 gene was replaced by human HLA-A2 gene.
Validation Data
Figure 1. Detection of HLA-A2 expression in spleen and intestine by RT-PCR.
Wild type: only one band at 400 bp with primers F1/R1 (mH2-D1); Heterozygous: one band at 400 bp with primers F1/R1 (mH2-D1) and one band at 664 bp with primers F2/R2 (hHLA-A2); Abbr.. M