ASHU-200279, 4-1BB & PD-1, C57BL/6-Tnfrsf9tm2(TNFRSF9)Pdcd1em1(hPDCD1)/Asc, Humanized, GENE Synonyms Ly101, ILA; Ly63; 4-1BB; Cd137; CDw137; AA408498; AI325004; A930040I11Rik, Human Orthologs TNFRSF9, PDCD1, ENSMUSG00000028965, ENSMUSG00000026285, 1101059, 104879, 21942, 18566, 21942, 18566, Coat Color Black, Immunotherapy, cancer research, drug screening
4-1BB (2) & PD-1
4-1BB (2) & PD-1
Nomenclature
Cat. NO.ASHU-200279
Strain State
Gene Summary:
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| Human Orthologs | /m/o/mouse-model-20200122_116.jpg |
Research Application:
Description:
Humanized Gene Knock-in Strategy
Validation Data: 4-1BB (2)
Figure 1. Expression of humanized CD137 (4-1BB) in the activated spleen lymphocytes of heterozygous humanized 4-1BB mice is detected by FACS. The spleen lymphocytes of heterozygous humanized 4-1BB mice were activated by anti-CD3 and anti-CD28 for 48 hours