The endogenous mouse Il21 gene was replaced by human IL21 gene.
Validation Data
Figure 1. Detection of IL21 expression in splenocyte by RT-PCR.
Wild type: only one band at 272 bp with primers F1/R1(mIl21); Homozygous: only one band at 304 bp with primers F2/R2(hIL21); Abbr. M