Immunotherapy
SIRPA (2) & CD47 & PD-1
SIRPA (2) & CD47 & PD-1
Nomenclature
C57BL/6 - Sirpatm2(hSIRPA)Cd47em1(hCD47) Pdcd1em1(hPDCD1)/Asc
Cat. NO.ASHU-2000090
Strain State
Gene Summary:
| Synonyms | Bit, P84, SIRP, SHP-1, CD172a, Ptpns1, SHPS-1, AI835480, IAP, Itgp, Ly101 |
| NCBI ID | 19261, 16423, 18566 |
| MGI ID | 108563, 96617, 104879 |
| Ensembl ID | ENSMUSG00000037902, ENSMUSG00000055447, ENSMUSG00000026285 |
| Human Orthologs | SIRPA, CD47, PDCD1 |
Research Application:
Description:
This SIRPA，CD47 and PD-1 triple Knock-in strain is established by crossing hSIRPA, hCD47 and hPD-1 mice of three humanized strains together. These triple Knock-in mouse models can be useful for evaluating the efficacy of potential immunotherapy drug combinations