CCR8 (2)

Nomenclature
1201402
Cat. NO.ASHU-2000054
Strain State

Gene Summary:

SynonymsENSMUSG00000042262
NCBI IDCCR8
MGI IDC57BL/6
Ensembl ID12776
Human OrthologsImmunotherapy, drug screening

Research Application:

CCR8 (2)

Description:

Humanized Strategy

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Humanized CCR8 Protein Sequence

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Alignment of Human and Humanized CCR8 Protein

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Overall Proportions of Immune Cells in the Blood of Humanized CCR8 Mouse

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Overall Proportions of Immune Cells in the Blood of Humanized CCR8 Mouse

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Overall Proportions of Immune Cells in the Blood of Humanized CCR8 Mouse

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hCCR8 Expression Validation in Humanized CCR8

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Binding of Anti-hCCR8 to Spleen-derived T cells in Humanized CCR8 Mouse

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Binding of Anti-hCCR8 to Spleen-derived T cells in Humanized CCR8 Mouse

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In vivo Validation of Humanized CCR8 Mice

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Figure 1. In vivo validation of humanized CCR8 mice. Humanized CCR8 mice were inoculated with MC38 colon cancer cells