CCR8 (2)
CCR8 (2)
CCR8 (2)
Nomenclature
1201402
Cat. NO.ASHU-2000054
Strain State
Gene Summary:
| Synonyms | ENSMUSG00000042262 |
| NCBI ID | CCR8 |
| MGI ID | C57BL/6 |
| Ensembl ID | 12776 |
| Human Orthologs | Immunotherapy, drug screening |
Research Application:
Description:
Humanized Strategy

Humanized CCR8 Protein Sequence

Alignment of Human and Humanized CCR8 Protein

Overall Proportions of Immune Cells in the Blood of Humanized CCR8 Mouse

Overall Proportions of Immune Cells in the Blood of Humanized CCR8 Mouse

Overall Proportions of Immune Cells in the Blood of Humanized CCR8 Mouse

hCCR8 Expression Validation in Humanized CCR8

Binding of Anti-hCCR8 to Spleen-derived T cells in Humanized CCR8 Mouse

Binding of Anti-hCCR8 to Spleen-derived T cells in Humanized CCR8 Mouse

In vivo Validation of Humanized CCR8 Mice

Figure 1. In vivo validation of humanized CCR8 mice. Humanized CCR8 mice were inoculated with MC38 colon cancer cells