The endogenous mouse Ifngr1 gene was replaced by human IFNGR1 gene.
Validation Data
Figure 1. Detection of IFNGR1 expression by RT-PCR. Wild type: only one band at 271 bp with primers F2/R2 (mIfngr1); Homozygous: only one band at 296 bp with primers F1/R1 (hIFNGR1); Abbr.. M