The endogenous mouse Il2ra gene was replaced by human IL2RA gene.
Validation Data
Figure 1. Detection of IL2RA expression by RT-PCR.
Wild type: only one band at 203 bp with primers F2/R2 (mIl2ra); Homozygous: only one band at 251 bp with primers F1/R1 (hIL2RA); Abbr.. M