PD-1 & PD-L1 & PDCD1LG2

Nomenclature
C57BL/6 - Pdcd1lg2em1(hPDCD1LG2)Pdcd1em1(hPDCD1)Cd274em1(hPD-L1)/Asc
Cat. NO.ASHU-190060
Strain State

Gene Summary:

SynonymsPD-1, Pdc1, Ly101, B7h1, Pdl1, Pdcd1l1, Pdcd1lg1, A530045L16Rik, Btdc, B7-DC, PD-L2, 730015O22Rik
NCBI ID18566, 60533, 58205
MGI ID104879, 1926446, 1930125
Ensembl IDENSMUSG00000026285, ENSMUSG00000016496, ENSMUSG00000016498
Human OrthologsPDCD1, CD274, PDCD1LG2

Research Application:

Immunotherapy, cancer research, drug screening

Description:

The endogenous mouse Pd-1/Pd-l1/Pdcd1lg2 gene was replaced by human PD-1/PD-L1/PDCD1LG2 gene via CRISPR/Cas mediated recombination.