Immunotherapy
PD-L1 & TIM3
PD-L1 & TIM3
Nomenclature
C57BL/6J - Cd274em1(hPD - L1)Havcr2em1(hHAVCR2)/Asc
Cat. NO.ASHU-190056
Strain State
Gene Summary:
| Synonyms | B7h1， Pdl1， Pdcd1l1，Pdcd1lg1， A530045L16Rik,Tim3, TIM-3, Timd3 |
| NCBI ID | 60533; 171285 |
| MGI ID | 1926446;2159682 |
| Ensembl ID | ENSMUSG00000016496;ENSMUSG00000020399 |
| Human Orthologs | CD274; HAVCR2 |
Research Application:
Description:
This PD-L1 and TIM3 double Knock-in strain is established by crossing PD-L1-HU and TIM3-HU mice together. These double double Knock-in mouse models can be useful for evalueting the efficacy of potential immunotherapy drug combinations.