PD-L1 & SEMA4D

Nomenclature
C57BL/6J - Cd274em1(hPD - L1) Sema4dem1(hSEMA4D)/Asc
Cat. NO.ASHU-190034
Strain State

Gene Summary:

SynonymsB7h1， Pdl1， Pdcd1l1，Pdcd1lg1， A530045L16Rik;CD100, Semaj, Semcl2, coll-4, Semacl2
NCBI ID60533;20354
MGI ID1926446;109244
Ensembl IDENSMUSG00000016496;ENSMUSG00000021451
Human OrthologsCD274;SEMA4D

Research Application:

Immunotherapy

Description:

This PD-L1 and SEMA4D double Knock-in strain is established by crossing PD-L1-HU and SEMA4D-HU mice together. These double double Knock-in mouse models can be useful for evalueting the efficacy of potential immunotherapy drug combinations.