PD-1 & SEMA4D

Nomenclature
C57BL/6J - Pdcd1em1(hPDCD1) Sema4dem1(hSEMA4D)/Asc
Cat. NO.ASHU-190033
Strain State

Gene Summary:

SynonymsLy101;CD100, Semaj, Semcl2, coll-4, Semacl2
NCBI ID18566;20354
MGI ID104879;109244
Ensembl IDENSMUSG00000026285;ENSMUSG00000021451
Human OrthologsPDCD1;SEMA4D

Research Application:

Immunotherapy

Description:

This PD-1 and SEMA4D double Knock-in strain is established by crossing PD-1-HU and SEMA4D-HU mice together. These double double Knock-in mouse models can be useful for evalueting the efficacy of potential immunotherapy drug combinations.